In a little bit of  battletesting, Ghost Recon works almost flawlessly under Linux. All that I have to do, is set it to emulate a virtual desktop of my screen size (with the game to match), hide my panels, and leave anything I want to access within alt+tab range.

There's some rendering bugs or performance optimizations with WINEs desktop emulation window, that are apparent because of (sigh) the game changing resolutions when it comes to menus. This is something that pisses me off about game developers (particularly from RSE), don't hard code shit !